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Rankings
| Rank | Team | Trend | Last Week | This Week |
|---|
| 1. | Alabama | – | W 59-0 Mercer | @ #13 Florida |
| 2. | Clemson | – | W 68-0 South Carolina State | Georgia Tech |
| 3. | Ohio State | +1 | W 29-11 #12 Oregon | Tulsa |
| 4. | Oklahoma | -1 | W 61-0 Western Carolina | Nebraska |
| 5. | Georgia | – | W 70-0 UAB | South Carolina |
| 6. | Iowa State | +1 | W 36-29 #15 Iowa | @ UNLV |
| 7. | Texas A&M | -1 | W 31-17 vs. Colorado | New Mexico |
| 8. | Cincinnati | – | W 50-3 Murray State | @ #21 Indiana |
| 9. | Notre Dame | – | W 30-0 Toledo | Purdue |
| 10. | Wisconsin | – | W 24-15 Eastern Michigan | bye |
| 11. | North Carolina | – | W 49-30 Georgia State | Virginia |
| 12. | USC | +2 | W 45-20 Stanford | @ Washington State |
| 13. | Florida | – | W 24-0 @ South Florida | #1 Alabama |
| 14. | Oregon | -2 | L 11-29 @ #4 Ohio State | Stony Brook |
| 15. | Texas | +1 | W 27-26 (OT) @ Arkansas | Rice |
| 16. | Iowa | -1 | L 29-36 @ #7 Iowa State | Kent State |
| 17. | UCLA | – | bye | Fresno State |
| 18. | LSU | – | W 46-8 McNeese | Central Michigan |
| 19. | Miami (FL) | +2 | W 56-25 Appalachian State | Michigan State |
| 20. | Coastal Carolina | – | W 38-9 Kansas | @ Buffalo |
| 21. | Indiana | – | W 60-7 Idaho | #8 Cincinnati |
| 22. | Utah | +1 | W 37-16 @ BYU | @ San Diego State |
| 23. | Arizona State | +1 | W 35-0 UNLV | @ BYU |
| 24. | Ole Miss | +1 | W 68-0 Austin Peay | Tulane |
| 25. | Michigan | NR | W 31-18 #19 Washington | Northern Illinois |
| Dropped Out: | #19 Washington | | | |
Schedule
2021 Week 3 Scores
| Date | Home | | Away | |
| Thursday 9/16 | Louisiana | 42 | Ohio | 19 |
| Friday 9/17 | Louisville | 44 | UCF | 29 |
| Friday 9/17 | Illinois | 18 | Maryland | 28 |
| Saturday 9/18 | Kentucky | 62 | Chattanooga | 0 |
| Saturday 9/18 | Missouri | 34 | Southeast Missouri State | 24 |
| Saturday 9/18 | Tennessee | 59 | Tennessee Tech | 11 |
| Saturday 9/18 | #7 Texas A&M | 57 | New Mexico | 0 |
| Saturday 9/18 | #19 Miami | 37 | Michigan State | 19 |
| Saturday 9/18 | Pittsburgh | 35 | Western Michigan | 21 |
| Saturday 9/18 | Syracuse | 26 | Albany | 14 |
| Saturday 9/18 | Temple | 16 | Boston College | 58 |
| Saturday 9/18 | West Virginia | 24 | Virginia Tech | 25 |
| Saturday 9/18 | #21 Indiana | 13 | #8 Cincinnati | 35 |
| Saturday 9/18 | #25 Michigan | 51 | Northern Illinois | 26 |
| Saturday 9/18 | #4 Oklahoma | 55 | Nebraska | 16 |
| Saturday 9/18 | Army | 6 | UConn | 32 |
| Saturday 9/18 | Buffalo | 38 | #20 Coastal Carolina | 42 |
| Saturday 9/18 | Colorado | 28 | Minnesota | 36 |
| Saturday 9/18 | Kansas State | 48 | Nevada | 23 |
| Saturday 9/18 | #9 Notre Dame | 42 | Purdue | 24 |
| Saturday 9/18 | #13 Florida | 28 | #1 Alabama | 24 |
| Saturday 9/18 | Louisiana Tech | 22 | SMU | 44 |
| Saturday 9/18 | #2 Clemson | 56 | Georgia Tech | 3 |
| Saturday 9/18 | Wake Forest | 25 | Florida State | 33 |
| Saturday 9/18 | #16 Iowa | 38 | Kent State | 19 |
| Saturday 9/18 | #3 Ohio State | 41 | Tulsa | 15 |
| Saturday 9/18 | Rutgers | 34 | Delaware | 12 |
| Saturday 9/18 | Kansas | 3 | Baylor | 42 |
| Saturday 9/18 | Miami (OH) | 36 | LIU | 0 |
| Saturday 9/18 | Akron | 55 | Bryant | 20 |
| Saturday 9/18 | Appalachian State | 64 | Elon | 16 |
| Saturday 9/18 | Oregon State | 40 | Idaho | 16 |
| Saturday 9/18 | Washington State | 32 | #12 USC | 53 |
| Saturday 9/18 | UMass | 7 | Eastern Michigan | 44 |
| Saturday 9/18 | Wyoming | 37 | Ball State | 23 |
| Saturday 9/18 | Arkansas | 30 | Georgia Southern | 20 |
| Saturday 9/18 | Memphis | 32 | Mississippi State | 26 |
| Saturday 9/18 | Duke | 3 | Northwestern | 29 |
| Saturday 9/18 | Toledo | 38 | Colorado State | 0 |
| Saturday 9/18 | California | 44 | Sacramento State | 21 |
| Saturday 9/18 | Washington | 60 | Arkansas State | 26 |
| Saturday 9/18 | Bowling Green | 18 | Murray State | 0 |
| Saturday 9/18 | Marshall | 42 | East Carolina | 26 |
| Saturday 9/18 | UTSA | 42 | Middle Tennessee | 7 |
| Saturday 9/18 | Florida Atlantic | 42 | Fordham | 17 |
| Saturday 9/18 | Liberty | 44 | Old Dominion | 7 |
| Saturday 9/18 | #5 Georgia | 42 | South Carolina | 8 |
| Saturday 9/18 | Georgia State | 36 | Charlotte | 52 |
| Saturday 9/18 | Texas Tech | 16 | FIU | 18 |
| Saturday 9/18 | Southern Mississippi | 31 | Troy | 34 |
| Saturday 9/18 | Houston | 49 | Grambling | 11 |
| Saturday 9/18 | South Florida | 25 | Florida A&M | 3 |
| Saturday 9/18 | Texas State | 58 | Incarnate Word | 0 |
| Saturday 9/18 | San Diego State | 18 | #22 Utah | 19 (OT) |
| Saturday 9/18 | North Texas | 22 | UAB | 15 |
| Saturday 9/18 | Penn State | 38 | Auburn | 22 |
| Saturday 9/18 | #18 LSU | 51 | Central Michigan | 12 |
| Saturday 9/18 | NC State | 41 | Furman | 9 |
| Saturday 9/18 | #11 North Carolina | 39 | Virginia | 6 |
| Saturday 9/18 | #14 Oregon | 64 | Stony Brook | 6 |
| Saturday 9/18 | Air Force | 20 (OT) | Utah State | 17 |
| Saturday 9/18 | #24 Ole Miss | 41 | Tulane | 30 |
| Saturday 9/18 | Vanderbilt | 23 (OT) | Stanford | 22 |
| Saturday 9/18 | #15 Texas | 47 | Rice | 27 |
| Saturday 9/18 | UL Monroe | 44 | Jackson State | 18 |
| Saturday 9/18 | South Alabama | 35 | Alcorn State | 3 |
| Saturday 9/18 | New Mexico State | 41 | South Carolina State | 30 |
| Saturday 9/18 | Boise State | 21 | Oklahoma State | 28 |
| Saturday 9/18 | Arizona | 42 | Northern Arizona | 0 |
| Saturday 9/18 | BYU | 35 | #23 Arizona State | 45 |
| Saturday 9/18 | UNLV | 6 | #6 Iowa State | 56 |
| Saturday 9/18 | #17 UCLA | 43 | Fresno State | 29 |
| Saturday 9/18 | Hawai'i | 21 | San José State | 41 |