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Rankings
| Rank | Team | Trend | Last Week | This Week |
|---|
| 1. | Clemson | – | W 36-3 @ Syracuse | @ #24 Pittsburgh |
| 2. | Ohio State | +1 | Bye | @ Indiana |
| 3. | Texas A&M | +1 | W 45-0 @ Missouri | South Carolina |
| 4. | Iowa State | +2 | W 48-32 @ Kansas State | #22 Oklahoma State |
| 5. | Arizona State | +4 | W 25-24 @ #14 Utah | Bye |
| 6. | Cincinnati | +1 | W 35-11 UCF | @ Navy |
| 7. | North Carolina | +1 | W 31-24 Miami (FL) | Bye |
| 8. | Oklahoma | -6 | L 27-37 #24 TCU | @ Kansas |
| 9. | Auburn | +1 | W 16-6 @ Arkansas | Bye |
| 10. | Florida | -5 | L 41-44 (OT) @ #25 LSU | Bye |
| 11. | Texas | +1 | W 32-11 #16 Oklahoma State | Bye |
| 12. | Oregon | +1 | W 41-14 California | @ UCLA |
| 13. | TCU | +11 | W 37-27 @ #2 Oklahoma | West Virginia |
| 14. | Wisconsin | -3 | W 18-8 Army | @ Purdue |
| 15. | Utah | -1 | L 24-25 #9 Arizona State | @ Oregon State |
| 16. | Penn State | -1 | Bye | Illinois |
| 17. | LSU | +8 | W 44-41 (OT) #5 Florida | @ Ole Miss |
| 18. | Alabama | -1 | W 45-21 @ Mississippi State | Tennessee |
| 19. | Georgia | -1 | W 48-11 Kentucky | Bye |
| 20. | Coastal Carolina | -1 | Bye | @ Appalachian State |
| 21. | Michigan | -1 | Bye | Northwestern |
| 22. | Oklahoma State | -6 | L 11-32 @ #12 Texas | @ #4 Iowa State |
| 23. | Washington | -1 | W 45-33 UCLA | @ Arizona |
| 24. | Pittsburgh | NR | W 24-23 (OT) @ Virginia Tech | #1 Clemson |
| 25. | NC State | NR | W 46-31 @ Boston College | @ Miami (FL) |
| Dropped Out: | #21 Virginia Tech | #23 Notre Dame | | |
Schedule
| Date | Home | | Away | |
| Wednesday 10/20 | Appalachian State | 49 | #20 Coastal Carolina | 28 |
| Thursday 10/21 | Charlotte | 23 | Florida Atlantic | 26 |
| Thursday 10/21 | SMU | 31 | Tulane | 43 |
| Thursday 10/21 | Arkansas State | 41 | Louisiana | 23 |
| Thursday 10/21 | UNLV | 32 | San José State | 39 |
| Friday 10/22 | UConn | 26 | Middle Tennessee | 27 |
| Friday 10/22 | UCF | 39 | Memphis | 23 |
| Friday 10/22 | Utah State | 22 | Colorado State | 9 |
| Friday 10/22 | Arizona | 30 | #23 Washington | 38 (OT) |
| Saturday 10/23 | #16 Penn State | 45 | Illinois | 0 |
| Saturday 10/23 | Army | 32 | Wake Forest | 24 |
| Saturday 10/23 | Navy | 18 | #6 Cincinnati | 33 |
| Saturday 10/23 | #21 Michigan | 25 | Northwestern | 7 |
| Saturday 10/23 | #13 TCU | 13 | West Virginia | 16 |
| Saturday 10/23 | Vanderbilt | 26 | Mississippi State | 34 |
| Saturday 10/23 | Louisville | 52 | Boston College | 22 |
| Saturday 10/23 | #4 Iowa State | 39 | #22 Oklahoma State | 41 |
| Saturday 10/23 | Bowling Green | 34 | Eastern Michigan | 37 |
| Saturday 10/23 | Florida State | 36 | UMass | 0 |
| Saturday 10/23 | Ohio | 47 | Kent State | 33 |
| Saturday 10/23 | Georgia State | 46 | Texas State | 22 |
| Saturday 10/23 | Minnesota | 40 | Maryland | 36 |
| Saturday 10/23 | Wyoming | 38 | New Mexico | 27 |
| Saturday 10/23 | #3 Texas A&M | 37 | South Carolina | 6 |
| Saturday 10/23 | Miami | 43 | #25 NC State | 22 |
| Saturday 10/23 | Purdue | 33 | #14 Wisconsin | 29 |
| Saturday 10/23 | Central Michigan | 24 (OT) | Northern Illinois | 17 |
| Saturday 10/23 | UCLA | 37 | #12 Oregon | 25 |
| Saturday 10/23 | Indiana | 27 | #2 Ohio State | 38 |
| Saturday 10/23 | Texas Tech | 51 | Kansas State | 17 |
| Saturday 10/23 | California | 25 | Colorado | 10 |
| Saturday 10/23 | UAB | 30 | Rice | 7 |
| Saturday 10/23 | Ball State | 28 | Miami (OH) | 16 |
| Saturday 10/23 | Akron | 10 | Buffalo | 24 |
| Saturday 10/23 | Houston | 36 | East Carolina | 40 |
| Saturday 10/23 | Arkansas | 63 | Arkansas-Pine Bluff | 0 |
| Saturday 10/23 | Virginia Tech | 47 | Syracuse | 3 |
| Saturday 10/23 | North Texas | 38 | Liberty | 33 |
| Saturday 10/23 | UL Monroe | 19 | South Alabama | 22 |
| Saturday 10/23 | FIU | 36 | Western Kentucky | 21 |
| Saturday 10/23 | Louisiana Tech | 38 | UTSA | 27 |
| Saturday 10/23 | Air Force | 41 | San Diego State | 16 |
| Saturday 10/23 | Ole Miss | 44 | #17 LSU | 25 |
| Saturday 10/23 | Fresno State | 41 (OT) | Nevada | 40 |
| Saturday 10/23 | South Florida | 27 | Temple | 23 |
| Saturday 10/23 | Notre Dame | 48 | USC | 10 |
| Saturday 10/23 | #24 Pittsburgh | 32 | #1 Clemson | 55 |
| Saturday 10/23 | Kansas | 11 | #8 Oklahoma | 45 |
| Saturday 10/23 | Toledo | 30 | Western Michigan | 10 |
| Saturday 10/23 | #18 Alabama | 41 | Tennessee | 16 |
| Saturday 10/23 | Virginia | 28 | Georgia Tech | 42 |
| Saturday 10/23 | Washington State | 30 | BYU | 31 |
| Saturday 10/23 | Oregon State | 17 | #15 Utah | 52 |
| Saturday 10/23 | Hawai'i | 34 | New Mexico State | 10 |